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Conventional DCs from male and female lupus-prone B6.NZM Sle1/Sle2/Sle3 mice express an IFN signature and have a higher immunometabolism that are enhanced by estrogen

Evaluation on liver enzymes revealed constitutive induction of CYP2E1 and ALDH1A1 in untreated GCLM KO mice

Tyrosinase is an integral enzyme in melanogenesis (the process by which melanin is produced) Inhibition of this enzyme significantly affects the levels of melanin (the pigment that imparts color to your skin, the higher the levels darker the skin)

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