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"With lower insulin doses, individuals may be more likely to have ketosis, raising the concern for DKA

Hypoglycemia: While less common with GLP-1 receptor agonists like semaglutide compared to some other diabetes medications, hypoglycemia (low blood sugar) can still occur

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[9] Additionally, the appetite suppression and early satiety caused by GLP-1 agonists may result in reduced food and fluid intake, further compromising electrolyte status