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Use: To reduce the risk of sustained decline in eGFR, end-stage kidney disease, cardiovascular death, and hospitalization in adults with chronic kidney disease that is at risk of progression

Each of the functional IDH3 enzymes is a heterotetramer composed of three different subunits identified as the , , and subunits

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"We're all holding our breath a little bit," said Peter Koshland, who teaches clinical pharmacy at UC San Francisco, "and just hoping that nobody gets hurt."