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Nutritional counseling and close monitoring are vital for patients taking both medications to prevent malnutrition

In animal models, GLP-1R agonists prevent capillary rarefaction and microvascular barrier dysfunction and reduce apoptosis and reactive oxygen species in microvascular endothelial cells, contributing to improved organ function and reduced progression of microvascular complications [162]

26 UC is a chronic inflammatory disease that usually manifests itself clinically as a slowly progressive process and can be broadly divided into four stages

Current evidence remains limited, with most clinical experience coming from case reports and small observational studies rather than large randomized trials