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Genotoxicity testing, which evaluates whether a compound can damage DNA, found no evidence that 5-amino-1mq causes genetic damage

1 Introduction Multiple myeloma (MM), a hematologic malignancy characterized by clonal proliferation of bone marrow plasma cells, manifests clinically through CRAB criteria: hypercalcemia, renal dysfunction, anemia, and osteolytic lesions (van de Donk et al., 2021

cardiovascular and renal benefits observed in trials have broadened clinician interest

The studys authors noted that increases in GH and IGF-I levels produced by CJC-1295 DAC were dose-dependent, meaning that in the context of that particular study, higher doses of CJC-1295 produced greater rises in GH and IGF-1 levels than lower doses