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No evidence shows these products produce clinically meaningful metabolic effects or significant changes in endogenous GLP-1 levels

Patients with chronic kidney disease (eGFR below 60 mL/min/1.73m), those taking ACE inhibitors, ARBs, or potassium-sparing diuretics, and individuals with heart failure require regular potassium monitoring regardless of Mounjaro use

We refer readers to Tables C-G2 and C-G3 in the CY 2026 PFS proposed rule for more information regarding the proposed measures and scoring methodology for the MIPS Promoting Interoperability performance category, including the Security Risk Analysis measure (90 FR 32737 through 32744)

Patients should follow the advice of their healthcare provider on whether to discontinue semaglutide before a colonoscopy temporarily