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The 2011 discovery cohort was sampled years prior to initial proteomics experimentation, however the sample size ( n = 60) was sufficient to detect moderate to large differences between groups

This behavior of the GS flux is caused by the competition between the higher inhibition of GS and GCL by GSH and the higher stimulation of GCL by estradiol [Figure 2]

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Statements Data availability statement The RNA sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE316736