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The primary outcome is to identify the maximum dose tolerated, and the second aim is to evaluate neurological outcome

In this context, melittin has been shown to impede in vitro and in vivo HCC cell movement via lowering Rac1-dependent processes (Haque et al., 2023)

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(Skinner et al., 2014) Acamprosate modulates neural transmission from GABA and NMDA receptors to reduce withdrawal symptoms, (Kalk and LingfordHughes, 2014) whereas naltrexone, an opioid receptor antagonist, interferes with the reward pathway activated in AUD