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Surprisingly, compared with the ferroptosis inducers RSL3 and erastin, ACE significantly increased the intracellular Fe 2+ levels (Fig

Reduced taurine/hypotaurine turnover in OVX plasma therefore signifies increased oxidative burden and a heightened proinflammatory state

Cardiovascular diseases Given the critical involvement of autophagy in cardiovascular diseases, such as myocardial ischemic and reperfusion injury, cardiomyopathy, myocardial infarction, and heart failure 138,139,140,141,142 , the roles of lysosomes as the terminal sites of the autophagic process are indispensable

Oral glutathione has relatively poor bioavailability (only 1015% absorption in the gut), so slowed emptying may not meaningfully improve or worsen its absorption