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Furthermore, in rat models, the GLP-1 RA exendin-4 was found to alleviate ischemiareperfusion injury in skin flaps by upregulating Gpx4 expression, thereby inhibiting ferroptosis [73]

The drug is a so-called tri-agonist, meaning it simultaneously stimulates three different hormone receptors: GLP-1 : Lowers appetite and improves blood sugar levels

Ashley Koff, RD 00:45:16 You know, that gets me into the land, a little bit of Cox two inhibitors and some of the places where weve unfortunately learned from patient populations that when you skip over something, it might seem like, oh, less side effects or anything that offers faster weight loss

They're small, fat-friendly, and active in microgram-to-low-milligram doses