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Edfalk S, Steneberg P, Edlund H (2008) Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion

The nausea typically peaks 24 to 48 hours after injection and improves as the week progresses

The intranasal administration of peptides for treating a disorders originating in the brain is not a novel concept, but only the vasopressin analog desmopressin has been used clinically by this route for several decades to treat diabetes insipidus (Kastin and Pan, 2006)