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Typical EE% ranges: (1) Hydrophobic drugs: 7095% (2) Hydrophilic compounds: 4080% (3) Nucleic acids (e.g., mRNA, siRNA): 6090% depending on method We use techniques such as ultrafiltration, Sephadex spin columns, and HPLC/UV analysis to quantify encapsulation efficiency with precision

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However, some patients report difficulty falling or staying asleep during treatment, raising questions about whether GLP-1 drugs directly cause insomnia or whether other factors play a role