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Indeed, nodose GLP-1R lentivirus-mediated knockdown increases postprandial glycemia 128 , and Glp1r Phox2b/ mice, which exhibit selective knockout of GLP-1R in the nodose ganglia, midbrain, and hindbrain, exhibit increased fasting levels of glucose, both highlighting a role for GLP-1 vagal afferent signaling in mediating glucose homeostasis 127

Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo

That said, combining the two can worsen side effects like nausea and vomiting, cause dangerous blood sugar drops, stall weight loss, and increase the risk of pancreatitis and kidney problems