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3 Results 3.1 Metabolome analysis reveals dominant impact of SLE on the pentose phosphate pathway, nucleotide, cysteine, and kynurenine metabolism Quantitative enrichment analysis of 258 measured metabolites revealed robust changes in the metabolome of SLE patients PBL relative to those of healthy controls matched for age within 10 years, gender, and ethnic background
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Combined with advancing age, poor lifestyle choices or environmental stressors, all of which reduce glutathione even further, poor health outcomes are likely
CD98 defines a metabolically flexible, proinflammatory subset of low-density neutrophils in systemic lupus erythematosus
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