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Extended 15-year follow-up studies showed that treatment prevented age-related impairment of physical endurance, normalized circadian rhythm of melatonin production, and improved carbohydrate and lipid metabolism markers

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B12 deficiency is one of the most common and most frequently overlooked nutritional deficiencies, affecting those on plant-based diets, adults over 50, individuals on certain medications, and anyone with reduced gastrointestinal absorption

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