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This enzyme normally helps your body process the medication you take, balancing out how much of it goes into your bloodstream

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Biochemical surrogate markers of hemolysis do not correlate with directly measured erythrocyte survival in sickle cell anemia

maintaining hydration is important Common side effects (affecting up to 1 in 10 people): Vomiting Constipation Due to slowed gastric emptying Abdominal pain or discomfort Reduced appetite This is partly how the medication aids blood glucose control Indigestion or acid reflux Fatigue or dizziness Hypoglycaemia (low blood sugar) Particularly when used with other diabetes medications such as sulphonylureas or insulin Gallbladder problems Including gallstones When to seek medical advice: Contact your GP or diabetes team promptly if you experience: Severe, persistent abdominal pain particularly if radiating to the back, as this could indicate pancreatitis (rare but serious)