how to gain glutathione Is the Master Antioxidant? Here’s What Science Says A Review of Dietary (Phyto)Nutrients

ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4(+) T cells in low arginine condition

Excited to share that the final chapter of my PhD thesis is now published in the Journal of Medicinal Chemistry ( Although reactivity with glutathione is commonly used as a proxy for metabolic liability of covalent drugs, in this work we show that the intrinsic reactivity (electrophilicity) of covalent warheads is not a reliable predictor of their in vivo metabolic susceptibility

Gonfloni et al, 2009

The -amino group of Lys 185 acts as a general base, abstracting a proton from the hydroxyl group at C-3 of 6-phosphogluconate