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CNS actions GLP-1R signaling plays a critical role in the maintenance of glucose homeostasis as deletion of the GLP-1R in mice results in impaired glucose tolerance (Scrocchi et al., 1996) and physiological levels of GLP-1 enhance meal-related insulin secretion in humans (Kreymann et al., 1987

Wegovy age limit Wegovy (semaglutide) is approved for use in adolescents aged 12 and older and adults of all ages

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