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By Karin Elgar Abstract Abstract Vitamin B12 (B12) is an essential cofactor in cellular metabolism adequate supplies are needed for normal blood formation and neurological function, and deficiency can therefore lead to macrocytic anaemia and neurological deficits

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Quantitative Real-Time PCR (qRT-PCR) was used to measure mRNA expression of SASP factors (IL-1, IL-6, TNF-, TGF-) in TM3 cells, normalizing data to GAPDH

For patients with chronic gut inflammation, IBD, or autoimmune skin conditions who have not found adequate resolution through existing approaches, KPV warrants a serious clinical conversation not as a replacement for current care, but as a precisely targeted addition to a supervised protocol