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AMPK inhibitor partially prevents MG-induced cell death and apoptosis We pre-treated cells with 10 M compound C (a selective AMPK inhibitor) in MG-treated cells

doi: 10.1111/j.1471-4159.2007.04773.x

V.MazulevskyE

In an experimental model of abdominal aortic aneurysm, topiramate markedly downregulated pro-inflammatory M1 macrophage activity, reduced the expression of TNF-, IL-1, and matrix metalloproteinase-9, and promoted a phenotypic shift of macrophages from M1 to M2, thereby mitigating pro-inflammatory activity and enhancing tissue repair processes (Attia et al., 2023)