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doi:10.1016/j.ejpain.2011.07.007

In the nervous system, the presence of GLP-1 receptors in the brainstem and their vagal connection suggests that the effects on taste may be secondary to central modulation rather than direct peripheral action (157, 170) but also, in vitro and clinical studies may suggest changes in perception of sweet, bitter and salt flavors as a reflection of GLP-1 on TBC (67, 178)

Association between glucagon-like peptide-1 receptor agonists and ovarian cancer survival: a population-based cohort study

Intranasal administration of the optimized formulation exhibited 5.5 times greater relative bioavailability than oral administration of the drug solution, which was attributed to the avoidance of the first-pass effect and enhanced drug permeation across the nasal mucosa