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513,514 Astrocytes from FMR1 knockout mouse model of fragile X syndrome were characterised by an enhanced secretion pf interleukin-6 and tenascin C, as well as by increased purinergic signalling

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Immunotherapies and cell therapies associated with senolytic activity Regulation of the immune system The senescent process directly impacts the cells in which this biological mechanism is activated but also the surrounding cells through the SASP or specific proteins expression at the plasma membrane

CS exposure was shown to lead to the increase of IL-1 and TNF- in BAL fluid, while GHK-Cu reduced the release of these inflammatory cytokines in BAL fluid (Figures 3B,C)