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Patients were randomized 1:1 to receive subcutaneous semaglutide 2.4 mg once weekly or placebo as an adjunct to standard-of-care therapy for CVD, such as cholesterol-modifying medications, antiplatelet therapies and antihypertensive agents

"Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial"

When applied or administered correctly, it penetrates deep into the skin to stimulate repair and regeneration at a cellular level

This is a result of both the pigment shift and the general reduction in oxidative stress, which keeps skin cells looking healthier for longer