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Without a transporter, they remain blocked in the cytoplasm and cannot be burned to produce energy

XI, Comprehensive Biochemistry, Vol 46

The specific pharmacological effects and associated mechanisms are detailed in Supplementary materials Table 2

If glucose readings are elevated, checking for ketones may be warranted, particularly if accompanied by symptoms such as nausea, vomiting, abdominal pain, rapid breathing, or confusion, which could indicate diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS) requiring urgent medical attention