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Anti-IGF-1 receptor (IGF-1R) monoclonal antibodies (mAbs) were developed for clinical use in treating advanced stage cancers 22,23,24 , including Ganitumab, which remains under investigation as a combination therapy in clinical trials targeting Rhabdomyosarcoma (NCT03041701) and Ewing Sarcoma (NCT02306161), for which it recently received orphan drug status

Fecal microbiota transplantation from IF mice improved EAE in immune-receptor mice fed a normal diet

This neural proliferation is observed after reperfusion in cerebral ischemia

Additionally, the combination treatment of V-9302 and anti-PD-1 antibody can improve antitumor immunity in a mouse breast cancer model, transforming cold tumors into hot tumors (Li Q