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It is clear from the above that the gut microbiota and its metabolites regulate brain function through multiple pathways, which provides us with the novel idea of treating CNS diseases by modulating the gut microbiota

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If there is no significant change in cholesterol, TG, and HDL-C levels, there will not be any changes in the LDL-C level.[ , ] However, supplementation with L-carnitine could probably decrease the LDL-C and TG levels by increasing the expression of the LDL-C receptor and LPL genes.[] The observed reduction in LDL-C levels may be due to the consumption of low-calorie diet and aerobic exercise along with the supplementation.[] Gonzlez-Ortiz et al

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