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This increase was accompanied by a significant shift in the balance between GABA and glutamate, with a relative 50% increase on the GABAergic side ( p = 0.025)

The classical inflammasome pathway involves multiple stages, including inflammasome assembly and activation, channel protein formation, and the maturation and secretion of pro-inflammatory cytokines (e.g., IL1B and IL18)

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Honokiol alleviates cognitive deficits of Alzheimers Disease (PS1V97L) transgenic mice by activating mitochondrial SIRT3