Melanocortins are peptide hormones that are proteolytically cleaved from their precursor molecule known as pro-opiomelanocortin (POMC) and post-translationally modified into melanocyte-stimulating hormones (-, - and -MSH) and adrenocorticotrophic hormone (ACTH) (Nakanishi et al, 1979
[DOI] [PubMed] [Google Scholar] 25.Leon-Castillo A., Chrisinger J.S.A., Panse G., Samdani R.T., Ingram D.R., Ravi V., Prieto V.G., Wang W.-L., Lazar A.J
These in vitro observations not only provide an initial basis for in vivo treatment regimens focusing on the stimulation of endogenous hepatic glutathione levels, but could also contribute to an optimization of treatment intervals to limit the risk of adverse effects when NFT is administered as an antibiotic
[DOI] [PMC free article] [PubMed] [Google Scholar] 31.American College of Obstetricians and Gynecologists Practice Bulletin