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Specifically, the integration of GOx-triggered H 2 O 2 self-supply, GSH depletion-amplified Fenton-like reactions, and DOX-mediated chemotherapy collaboratively improved the tumor microenvironment, exerting a crucial role in cancer eradication

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The study was conducted in a mouse model with BRAF and NRAS mutations, as well as wild-type melanoma xenografts and allografts of highly metastatic melanoma (222)

71.4% of patients achieved clinically meaningful regrowth Five out of seven patients (71.4%) achieved more than 10% top scalp area regrowth the study's threshold for clinically meaningful improvement