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These measures may be obtained using your Electronic Medical Records (EMR) or with assistance from the Health Data Coalition : % patients on B 12 % patients on folate % active patients with B 12 test in last year % active patients with folate test in last year % pregnant patients on folate/B 12 This process would count towards Mainpro+ credits or College of Physicians and Surgeons of British Columbia (CPSBC) accreditation processes

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Of note, prolonged IGF-1 stimulation has been associated with cellular senescence through functional interactions with thioredoxin-interacting protein (TXNIP) [67], highlighting the need for further studies to clarify the systemic safety profile of long-term treatment