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Glutamic acid decarboxylase (GAD) enzyme converts glutamate to GABA, which is then released from the presynaptic GABAergic neuron and acts on the post-synaptic neuron

Several gut bacteria, including species of Lactobacillus and Bifidobacterium , can produce or modulate levels of neurotransmitters such as serotonin, dopamine, and -aminobutyric acid (GABA), which are critical for mood regulation [2, 6]

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Final FDA rulemaking typically follows the committee vote by several months to a year