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It is NOT due to people with obesity not having enough willpower

Our results demonstrated that the phosphatidylinositol 3-kinase (PI3K)/AKT pathway participated in the GHK-induced upregulation of miR-146a-3p and miR-146a-3p/AQP4 interaction plays a role in the injury following ICH

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For example, Janus-type MNMs have structural asymmetry, and traditional sputtering processes for the asymmetric coating of Janus particles often lead to incomplete coverage or excessive accumulation owing to uneven plasma distribution, resulting in low yields and large batch variations [281, 282]