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3 A subsequent trial is currently enrolling adults with a body mass index (BMI) of at least 30, with a primary endpoint of weight loss following six months of therapy

Know the Prognosis: The report indicates that symptoms may resolve spontaneously after several weeks or, more definitively, upon discontinuation of the drug

After stopping MT-II, the tan persists 4-8 weeks and fades gradually as melanocytes turn over naturally

The authors reported statistically significant mean reductions in body weight from baseline across the retatrutide dose groups relative to placebo, with gastrointestinal adverse events the most frequently reported findings, consistent with the incretin-agonist class