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On this occasion, the authors expand our understanding of glutathione biology and identify extracellular glutathione (GSH), abundant in the tumour microenvironment, as an alternative source of essential amino acids to sustain tumour cell proliferation

Briefly, the treated cells were seeded at a precise density for overnight culture, washed with basic medium, and equilibrated at 37 C for 1 h

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Flavonoids may counteract this pathological process by promoting the transition of macrophages toward the anti-inflammatory M2 phenotype, thereby facilitating inflammation resolution and initiating tissue repair mechanisms