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Trial data showed that Saxenda , in combination with a reduced-calorie diet and increased physical activity, resulted in significantly greater weight loss in some patients than reduced-calorie diet and physical activity alone

Many vitamin deficiencies are a result of poor diet

In obesity, the gut microbiota is dysbiotic, and this dysbiosis is associated with blunted endogenous GLP-1 secretion, partly through downregulation of GLP-1R and nNOS expression in the enteric nervous system (Inagaki & Yamane, 2017)

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