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Consequently, regulatory agencies such as the FDA and EMA initiated safety reviews

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Thus, the cocaine-and amphetamine-regulated transcript (CART) has been reported to have an anorexic effect after intracerebroventricular administration [141], while CART injected directly into the paraventricular or arcuate nucleus of fasted rats increases food intake [142]

These findings highlight the complex and potentially tissue-specific effects of GLP-1 RAs on cancer development and progression, underscoring the need for further research to elucidate the underlying mechanisms and clinical implications