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6) Pro-Regenerative Crosstalk Human-centric reviews 9 detail how IGF-1 interacts with cytokines (e.g., IL-6) and niche signals to regulate repair dynamics, offering a systems-level explanation for why restoring IGF-1 signaling aligns with better recovery trajectories

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Moreover, phthalates antagonize the binding of T3 to thyroid receptor-, limiting T3 cell uptake, and disrupting sodium-iodine transporter transcription, lowering thyroxine (T4) and T3 levels in pregnant women and children (84, 85)

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