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Hepatic G6PD enzymatic activity is diminished in G6PD-deficient individuals (93), can be altered in non-deficient individuals by exogenous factors, such as insulin and high fat diets (94, 95), and can be upregulated to meet increased demand in states of physiologic stress

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Prior authorization for Zepbound for sleep apnea If your UnitedHealthcare plan covers Zepbound for sleep apnea, your prior authorization paperwork must show that you have: A BMI of 30 or higher Moderate-to-severe OSA with an apnea-hypopnea index (AHI) of at least 15 events per hour on either a polysomnogram or home sleep apnea test Tried to lose weight through diet at least once before without success Tried PAP therapy without success, or are currently using it but still experiencing symptoms of OSA Plans to use Zepbound with a reduced-calorie diet and increased physical activity If approved, the initial authorization lasts for six months

Zepbound is usually given once a week and can be given with or without meals at any time of the day