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This relationship supports the hypothesis that much of tirzepatide's anti-inflammatory benefit may be mediated through weight loss rather than direct receptor-mediated anti-inflammatory signaling, though controlled studies specifically addressing this question are limited

Their ability to improve metabolic health, reduce systemic inflammation, and lower surgical complication rates makes them valuable in optimizing patient outcomes

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Dehydration can affect kidney function, so keeping an eye on creatinine and eGFR levels is a good idea, especially if you have nausea or vomiting