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In addition, the lack of an endogenous equivalent of the HaloTag protein in mammalian cells minimizes the chance of detecting false positives or nonspecific interactions

The widespread and extensive use of gutkha, khaini, and zarda (cheaper and more accessible than cigarettes) has rendered smokeless tobacco an endemic affliction across rural and peri-urban India (198)

These mechanisms are believed to underpin its geroprotective effects 1