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This is primarily because overweight is often associated with hormonal disorders for instance, in the so-called polycystic ovary syndrome, which can impair fertility." And further: "When weight normalizes and metabolism improves, it has an overall positive effect on fertility

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By separating the lipolytic C-terminal region, researchers produced a compound with concentrated fat-metabolism activity and a significantly reduced side-effect profile compared to recombinant GH particularly with respect to insulin sensitivity and IGF-1 axis stimulation, which are primary concerns with full GH administration in research models