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As with any medication that affects glucose and appetite, people with diabetes or those on other blood-sugar-lowering medicines need close monitoring

GLP-1 Microdosing Chart & Schedule According to a 2,700-person real-world study presented at the 2025 European Congress on Obesity, participants achieved an average 16% weight loss over 64 weeks at microdose levels of semaglutide: Microdosing GLP-1 Weight Loss Results Microdose GLP-1 yields 5-10% body weight loss in year one versus 15-20% with full-dose treatment plans

Comparison with Other Weight Loss Medications Compared to other weight loss medications such as Orlistat, Phentermine, and Liraglutide, Semaglutide stands out due to its dual benefits of appetite regulation and blood sugar control