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CVD mortality in Latin America remains elevated (188 per 100,000 for men and 132 per 100,000 for women), driven by hypertension and obesity, with the overall burden projected to intensify by 2050 amid urbanization and aging [26] Sub-Saharan Africa bears the highest age-standardized CKD mortality (characteristic of low-SDI regions), alongside a rapidly escalating CVD burden fueled by population growth and urbanization [27]