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Up to an optimal concentration, the antioxidant machinery remained effective in mitigating stress, as evidenced by improved physiological and biochemical responses

When you are sleep-deprived, your body produces more ghrelin (the "hunger hormone") and less leptin (the "fullness hormone")

The allowance for investigators to use all available information (for example, concomitant medication) to assess glycemic category was primarily included to account for scenarios in which glucose-lowering medications were initiated during the trial that would confound glycemic category assessment if based purely on fasting plasma glucose or HbA 1c levels (for example, if a patient developed diabetes during the study and received a glucose-lowering drug that resulted in their glucose level being below the American Diabetes Association threshold for type 2 diabetes diagnosis)

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