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GIP receptor activation may modulate the dopamine-suppressing effects of GLP-1 receptor activation, effectively buffering the sexual side effects

Inspired by this idea long acting dual agonists were developed to treat type 2 diabetes and several obesity related health issues

doi: 10.1002/jat.4709 183 BartoliniDStabileAMMigniAGurradoFLiociGDe FrancoFet al

One of the primary effects of GLP-1 is its ability to reduce hunger and increase feelings of satiety, which is particularly noticeable in the early stages of treatment