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Other potential side effects of semaglutide injections include burning at injection sites on the skin, blistering, discoloration of the skin or yellow patches in your eyes or mouth, hives, infection, inflammation, itching sensation, lumps under the skin where you injected called lipohypertrophy, numbness around the lips and regions close to them due to injections too often in one area, pain or soreness around the injection site that lasts longer than 24 hours after injecting yourself with semaglutide which could last several days and rashes
However, the researchers did a sensitivity analysis of a 50 mg version and found that it was not as effective as tirzepatide in non-diabetic patients looking to lose weight
At the highest tirzepatide dose, the gap widened to more than double