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Oral bioavailability has not been characterized, and the compound's heptapeptide structure (773.89 Da) makes oral activity less likely than for the smaller Dihexa (504.66 Da), though not impossible given its modified sequence
Free radicals are highly reactive molecules produced as a by-product from biochemical processes that can drive inflammation and tissue damage and are often present in Autoimmune diseases eg
Concurrent use can significantly increase the risk of hypoglycemia
Repeated IV/IM doses indeed suggested efficacy for DFO in Alzheimers disease, but such invasive regimens are not practical long-term and carry significant risks
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