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In contrast, in a trial among more than 200 Chinese patients with various cancers who had peripheral neuropathy from previous chemotherapy, those who took ALC were more likely than those who took a placebo to have an improvement of at least one grade in their neuropathy

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Deiodinases (DIOs) regulate thyroid hormone metabolism by catalyzing the conversion of thyroid hormones from precursor thyroxine (T 4 ) to biologically active triiodothyronine (T 3 ) or inactive reverse T 3 (rT 3 ) 54

The animal data showed exactly that pattern, which is the signature of an energy expenditure effect layered on top of appetite control