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In vitro studies also suggested a relationship between IGF-I and LH-androgen production in rodents[125], through a direct effect on Leydig cells

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In clinical trials, patients lost an average of 10-15% of body weight over 68 weeks

Moreover, a comprehensive lipidomic analysis demonstrated that liraglutide significantly reduces various lipid species, such as triglycerides, ceramides, phosphatidylethanolamines and phosphatidylcholines [57]