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These cytokines are markers of chronic low-grade inflammation, the kind associated with accelerated biological aging, cardiovascular disease, neurodegeneration, and metabolic syndrome

However, the result faded after 3 months, which made the researchers debate whether the impact could be from the initial frequent provider visits, motivated lifestyle choices, or the excessive nausea and malaise experienced on initiation of GLP-1 receptor agonists, which could have reduced the alcohol intake during the first few months

People undergoing chemotherapy, taking immunosuppressive medications, living with HIV/AIDS, or dealing with other conditions that compromise immune function should consult their physician before starting any probiotic, including Pendulum

Research in animal models has shown promising results, with reductions in alcohol, nicotine, and opioid consumption